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Viewing: PUBH 6123 : Toxicology: Applications for Public Health Policy

Last approved: Fri, 18 Mar 2016 17:36:12 GMT

Last edit: Thu, 16 Apr 2015 21:37:45 GMT

Milken Institute School of Public Health
Public Health (PUBH)
PUBH
6123
Toxicology: Applications for Public Health Policy
Toxicology: Pubc Health Policy
201501
3
Course Type
Lecture
Default Grading Method
Letter Grade

No
No
PUBH 6004
Corequisites

24
George Gray
Frequency of Offering

Term(s) Offered

Are there Course Equivalents?
No
 
No
Fee Type


No


Toxicology as both a scientific discipline and a source of information for public health policy with respect to the regulation of foods, pesticides, drugs (pharmaceuticals), environmental chemical pollutants, and other chemicals that may affect human and environmental health. How chemicals interact with biological systems to produce adverse effects. The ways in which toxicologic information is developed and applied to regulatory decision making and the use of toxicology in regulatory risk assessment.
At the end of the course students should be able to: Apply key concepts in toxicology including: dose-response relationships; absorption, distribution, metabolism and excretion of xenobiotics; acute and chronic effects • Describe the biological basis for the adverse effects of toxicants on specific organs and tissues and identify specific compounds that interact with specific organs • Describe biological basis for the systemic effects of toxicants (e.g., carcinogenicity, genotoxicity, developmental toxicity) and identify specific compounds that elicit these effects. • Explain key aspects of toxicological tests as well as their strengths and weaknesses • Explain how risk assessment is used to translate toxicologic information for regulatory decisions including: evaluating a body of data and applying • Explain how risk assessment is used to translate toxicologic information for regulatory decisions including: evaluating a body of data and applying weight of evidence approaches; calculating and using the reference dose (RfD); calculating and using of cancer slope factors • Explain the role of scientific, economic, ethical, and political interests in development and implementation of human health and environmental health policy • Evaluate data and other information to characterize potential EOH hazards, sources of those hazards, potential for human exposure, and potential or actual health effects • Communicate with relevant stakeholder groups about environmental and
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Course Attribute


ebrunori (Fri, 19 Dec 2014 17:33:39 GMT): Update abbreviated course title and course summary
Key: 7775